Salmonella hides from your body by literally wearing your own immune system like a suit of armor.
This discovery reveals a 'molecular camouflage' where the bacteria steal a specific protein from your body to trick your defenses. By coating themselves in your own proteins, they can move through your system without being attacked by your innate immune response.
TraC Promotes Complement Evasion of Salmonella Enterica Serovar Choleraesuis by Recruiting Host C4b-binding Protein
SSRN · 6533072
Salmonella enterica serovar Choleraesuis (S. Choleraesuis) is a highly invasive zoonotic pathogen responsible for severe bloodstream infections, in which the complement system constitutes a major innate defense against circulating bacteria. However, the molecular basis underlying resistance of S. Choleraesuis to complement-mediated killing remains poorly understood. Here, whole-genome sequencing and pan-genome comparative analyses of S. Choleraesuis isolates exhibiting distinct serum-resistance