Trying to kill bacteria with antibiotics can accidentally 'train' them to survive the radiation we use to keep our food safe.
Researchers found that a single mutation allowing Salmonella to survive common drugs also makes it thousands of times tougher against sterilization. This means our battle against 'superbugs' could be creating bacteria that are nearly impossible to kill with traditional food safety methods.
Ciprofloxacin resistance in Salmonella drives cross-protection to UV-C and HHP via rpoD mutation
SSRN · 6546056
Antimicrobial resistance (AMR) remains a major public health concern, being the agri-food chain crucial in the emergence and dissemination of resistant pathogens such as Salmonella Typhimurium. Effective hygienization is key to prevent access of AMR bacteria into the agri-food chain. In this work, we investigated the consequences of ciprofloxacin (CIP) resistance acquisition in S. Typhimurium on tolerance to emerging non-thermal preservation technologies, including pulsed electric fields (PEF),